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. Author manuscript; available in PMC: 2019 Apr 24.

Published in final edited form as: JCSM Rapid Commun. 2019 Jan-Jun;2(1):e00075.

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This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. http://creativecommons.org/licenses/by/4.0/

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Figure 1. — In vivo treatment with carboplatin causes loss of lean mass in mice.

(a) Change in total body weight of mice. (b) Change in weight of gastrocnemius, tibialis anterior (TA), extensor digitorum longus (EDL), and soleus muscle. (c) Representative cross sections taken from the TA muscle in Non-tumor + vehicle, MDA-MB-231 + vehicle, Non-tumor + carboplatin, and MDA-MB-231 + carboplatin groups. (d) Quantitation of cross sectional area (CSA) from TA. (a) Two-way ANOVA (n=7), (b & d) One-way ANOVA with Tukey’s post-hoc test for multiple comparisons (b, n=7 and d, n=5); *p<0.05, **p<0.01, ***p<0.001 compared to control.