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. Author manuscript; available in PMC: 2019 Apr 24.

Published in final edited form as: JCSM Rapid Commun. 2019 Jan-Jun;2(1):e00075.

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This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. http://creativecommons.org/licenses/by/4.0/

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Figure 2. — In vivo treatment with carboplatin causes loss of trabecular bone in mice.

(a) Representative microCT scans of the femur and tibia in Non-tumor + vehicle, MDA-MB-321 + vehicle, Non-tumor + carboplatin, and MDA-MB-231 + carboplatin groups. Quantitation of Tb. BV/TV, Tb.N, Conn.D, Tb.Sp, and Tb.N of the (b) femur and (c) tibia for Non-tumor + vehicle, MDA-MB-321 + vehicle, Non-tumor + carboplatin, and MDA-MB-231 + carboplatin groups, (b & c) One-way ANOVA with Tukey’s post-hoc test for multiple comparisons (n=7), *p<0.05, **p<0.01, ***p<0.001, ****p<0.0001 compared to control group. #p<0.05 compared to MDA-MB-231 + vehicle.