Skip to main content
. Author manuscript; available in PMC: 2019 Apr 24.
Published in final edited form as: JCSM Rapid Commun. 2019 Jan-Jun;2(1):e00075.

Figure 4.

Figure 4.

Carboplatin reduced osteolytic lesion area and tumor burden.

(a) Representative X-ray images of hind limbs of mice 4 weeks after tumor inoculation and tumor inoculation with carboplatin treatment. (b) Quantitation of whole body osteolytic lesion area in MDA-MB-231 + vehicle and MDA-MB-231 + carboplatin groups. (c) Representative images of bone histology sections stained with H&E from Non-tumor + vehicle, MDA-MB-321 + vehicle, Non-tumor + carboplatin, and MDA-MB-231 + carboplatin groups. (d) Quantitation of tumor burden area in MDA-MB-231 + vehicle and MDA-MB-231 + carboplatin groups, (b & d) Student’s T-test (b, n=10 and d, n=5), #p<0.05, ##p<0.01 compared to MDA-MB-231 + vehicle.