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. 2019 Mar 22;10(24):2369–2383. doi: 10.18632/oncotarget.26792

Figure 1. Characterization of CD138.CAR-Ts.

Figure 1

(A) shows the schema of the CD138.CAR retroviral constructs (named CAR1, CAR2, CAR3 and CAR4) used to transduce activated T cells. (B) shows CD138.CAR expression evaluated by flow cytometry in control T cells (Ctr-Ts) and in T cells transduced with the four different CD138.CAR constructs. Upper panels are from one representative donor and lower graph shows cumulative data (n = 3-6). (C) shows the frequency of CD8 and and central memory subsets (CD45RA+CCR7+) gated on CD3+ cells for Ctr-Ts and CD138.CAR-Ts generated from healthy donors (n = 3-6).