Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Mar 22;10(24):2355–2368. doi: 10.18632/oncotarget.26760

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright: © 2019 Jonnalagadda et al.

This article is distributed under the terms of the Creative Commons Attribution License (CC-BY), which permits unrestricted use and redistribution provided that the original author and source are credited.

PMC Copyright notice

Most favorable compound 9 binding pose to human MCT1 and MCT4 were represented. (A) Cα ribbon homology structure of MCT1 with docked compound 9 (yellow) and binding site residues within 4.5 Å shown. (B) Cα ribbon homology structure of MCT4 with docked compound 9 (yellow) and binding site residues within 4.5 Å shown. (C) Overlay of MCT1 and MCT4 homology models and their respective best compound 9 docking pose. (D) Compound 9 (yellow) and residue forming its binding site in MCT1, all residues within 4.5 Å are shown. (E) Compound 9 (yellow) and residue forming its binding site in MCT1, all residues within 4.5 Å are shown. (F) Overlay of most favorable binding pose of compound 9 for MCT1 and MCT4 and all residues within 4.5 Å. Models were displayed with Chimera.