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. 2019 Mar 15;10(22):2189–2202. doi: 10.18632/oncotarget.26758

Figure 4. Effect of concurrent treatment with CDDP and 4D3 on growth of gastric cancer cells in nude mice.

Figure 4

In nude mice, MKN74 and TMK-1 tumors were treated with CDDP and/or 4D3. (A, B) Tumors were treated with CDDP (3 mg/kg BW) and/or 4D3 (1 mg/kg BW) on Day 1, 8, 15, and 22. (C, D) After MKN74 and TMK-1 tumors were grown to a diameter of 5 mm, they were treated with CDDP (3 mg/kg BW) and/or 4D3 (1 mg/kg BW) 3 times a week for 2 weeks. (E, F) Survival of mice with MKN74 or TMK-1 tumors (as seen in Figure 4C and 4D) were calculated using the Kaplan–Meier method. Bar, S.D.