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. 2019 Mar 19;10(23):2237–2251. doi: 10.18632/oncotarget.26787

Figure 1. Structure of SAB298.

Figure 1

The compound contains the pyrazolo[3,4-d]pyrimidine core structure, has the (3S, 4S) absolute configuration at the two stereogenic centers and features a substituted 1,2 dithiolane moiety that is unprecedented amongst kinase inhibitors. Its chemical name is (3S, 4S)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)methyl)-1,2-dithiolan-4-ol.