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(A) Western blot showing common inhibition of SFK (pSFK Y416) in YUSIV, 501 mel and YUROB melanoma cells in response to the two inhibitors, but pERK was inhibited only in response to UM-164 (pERK T202/Y204). (B) stimulation of pp38 T180/Y182 in YUSIV melanoma cells incubated for increasing periods of time with SAB298. (C) Trametinib, but not SAB298, inhibits pp38 T180/Y182.
