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. 2019 Mar 19;10(23):2237–2251. doi: 10.18632/oncotarget.26787

Table 2. KiNativ™ assay tests for SAB298 target protein*.

Kinase YUSIV YUSIK
YES1 <10 Not Present
SRC 31 Not Present
LYN 60 190
ABL2 87 240
ERBB3 290 240
MEK5 370 1500
CSK 420 910
ERBB2 410 530
mTOR 1,300 2,000
EGFR 1,300 530
LCK 1,400 Not Present
RIPK2 Not Present 20
MEK1 2,900 Not Present

*The results show IC50 in nM. Values were determined from 3-point dose response curve.