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. 2017 Jun 9;2017(6):CD009792. doi: 10.1002/14651858.CD009792.pub3

Taylor 1993.

Methods Prospective randomised trial; sealed, numbered envelopes; no sample size calculation
Participants Setting: UK
Women requiring labour induction due to prolonged pregnancy or pre‐eclampsia, 1 previous pregnancy delivered by lower segment CS, singleton in cephalic presentation, GA ≥ 37 weeks, BS < 9, no cephalopelvic disproportion anticipated
Interventions Amniotomy and IV oxytocin (n = 21) versus 2.5 mg vaginal PGE2 pessary, followed by amniotomy 3 h later + oxytocin (if necessary) 6 h later (n = 21)
Outcomes Induction to delivery time, analgesia, mode of delivery, uterine rupture
Notes Only half of the women included had an unfavourable cervix (BS < 6)
1 uterine rupture in PGE 2 group (after oxytocin) reported in abstract Sellers 1988 (see Taylor 1993)
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk "predetermined code envelope."
Allocation concealment (selection bias) Low risk Sealed envelopes
Blinding of participants and personnel (performance bias) 
 All outcomes High risk Not feasible
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk Blinding was not described in the report
Incomplete outcome data (attrition bias) 
 All outcomes Low risk Data of all women included were reported, no ITT analysis done
Selective reporting (reporting bias) Unclear risk Published report includes expected outcomes, but no outcome measures were prespecified in the methods section
Other bias Low risk The baseline characteristics were comparable between the groups