Comparison 1.
Oscillating devices (OD) versus positive expiratory pressure (PEP)
| Outcome or subgroup title | No. of studies | No. of participants | Statistical method | Effect size |
|---|---|---|---|---|
| 1 FEV₁ post‐intervention [% predicted] | 4 | Std. Mean Difference (IV, Fixed, 95% CI) | Subtotals only | |
| 1.1 Up to one week | 2 | 78 | Std. Mean Difference (IV, Fixed, 95% CI) | ‐0.03 [‐0.48, 0.41] |
| 1.2 Over one week and up to two weeks | 1 | 30 | Std. Mean Difference (IV, Fixed, 95% CI) | 0.12 [‐0.60, 0.84] |
| 1.3 Over two weeks and up to one month | 1 | 44 | Std. Mean Difference (IV, Fixed, 95% CI) | 0.49 [‐0.11, 1.09] |
| 2 FEV₁ change from baseline [% predicted] | 5 | Mean Difference (IV, Fixed, 95% CI) | Subtotals only | |
| 2.1 Over one week and up to two weeks | 1 | 22 | Mean Difference (IV, Fixed, 95% CI) | 9.37 [‐6.16, 24.90] |
| 2.2 Over two weeks and up to one month | 1 | 12 | Mean Difference (IV, Fixed, 95% CI) | ‐4.08 [‐12.82, 4.66] |
| 2.3 At one year | 3 | 162 | Mean Difference (IV, Fixed, 95% CI) | 1.54 [‐1.97, 5.06] |
| 3 FEF25‐75 post intervention [% predicted] | 4 | Mean Difference (IV, Fixed, 95% CI) | Subtotals only | |
| 3.1 Up to one week | 2 | 78 | Mean Difference (IV, Fixed, 95% CI) | 0.09 [‐9.33, 9.52] |
| 3.2 Over one week and up to two weeks | 1 | 30 | Mean Difference (IV, Fixed, 95% CI) | ‐1.0 [‐27.84, 25.84] |
| 3.3 Over two weeks and up to one month | 1 | 44 | Mean Difference (IV, Fixed, 95% CI) | ‐1.0 [‐3.95, 1.95] |
| 4 FEF25‐75 change from baseline [% predicted] | 5 | Mean Difference (IV, Fixed, 95% CI) | Subtotals only | |
| 4.1 Over one week and up to two weeks | 1 | 22 | Mean Difference (IV, Fixed, 95% CI) | 15.26 [‐10.12, 40.64] |
| 4.2 Over two weeks and up to one month | 1 | 12 | Mean Difference (IV, Fixed, 95% CI) | ‐20.07 [‐43.00, 4.86] |
| 4.3 At one year | 3 | 162 | Mean Difference (IV, Fixed, 95% CI) | 0.13 [‐4.46, 4.72] |
| 5 FVC post intervention [% predicted] | 4 | Mean Difference (IV, Fixed, 95% CI) | Subtotals only | |
| 5.1 Up to one week | 2 | 78 | Mean Difference (IV, Fixed, 95% CI) | ‐0.66 [‐8.71, 7.40] |
| 5.2 Over one week and up to two weeks | 1 | 30 | Mean Difference (IV, Fixed, 95% CI) | 3.0 [‐10.60, 16.60] |
| 5.3 Over two weeks and up to one month | 1 | 44 | Mean Difference (IV, Fixed, 95% CI) | 2.0 [‐0.09, 4.09] |
| 6 FVC change from baseline [% predicted] | 4 | Mean Difference (IV, Random, 95% CI) | Subtotals only | |
| 6.1 Over one week and up to two weeks | 1 | 22 | Mean Difference (IV, Random, 95% CI) | 5.40 [‐9.21, 20.01] |
| 6.2 At one year | 3 | 162 | Mean Difference (IV, Random, 95% CI) | 0.25 [‐6.14, 6.65] |
| 7 Sputum volume [ml] | 1 | Mean Difference (IV, Fixed, 95% CI) | Totals not selected | |
| 7.1 Up to 1 week | 1 | Mean Difference (IV, Fixed, 95% CI) | 0.0 [0.0, 0.0] | |
| 8 Sputum weight [g] | 1 | Mean Difference (IV, Fixed, 95% CI) | Totals not selected | |
| 8.1 Over one week and up to two weeks | 1 | Mean Difference (IV, Fixed, 95% CI) | 0.0 [0.0, 0.0] | |
| 9 Quality of life indices | 2 | Mean Difference (IV, Fixed, 95% CI) | Totals not selected | |
| 9.1 Quality of well being score | 1 | Mean Difference (IV, Fixed, 95% CI) | 0.0 [0.0, 0.0] | |
| 9.2 CRQ Disease specific interviewer administered questionnaire | 1 | Mean Difference (IV, Fixed, 95% CI) | 0.0 [0.0, 0.0] | |
| 9.3 CFQ: physical domain | 1 | Mean Difference (IV, Fixed, 95% CI) | 0.0 [0.0, 0.0] | |
| 9.4 CFQ: emotional domain | 1 | Mean Difference (IV, Fixed, 95% CI) | 0.0 [0.0, 0.0] | |
| 9.5 CFQ: treatment burden domain | 1 | Mean Difference (IV, Fixed, 95% CI) | 0.0 [0.0, 0.0] | |
| 9.6 CFQ: respiratory domain | 1 | Mean Difference (IV, Fixed, 95% CI) | 0.0 [0.0, 0.0] | |
| 9.7 CFQ: digestion/weight domain | 1 | Mean Difference (IV, Fixed, 95% CI) | 0.0 [0.0, 0.0] | |
| 10 Number of hospitalizations | 1 | Mean Difference (IV, Fixed, 95% CI) | Totals not selected | |
| 10.1 At one year | 1 | Mean Difference (IV, Fixed, 95% CI) | 0.0 [0.0, 0.0] | |
| 11 Pulmonary exacerbations (at 1 year) | 1 | Odds Ratio (M‐H, Fixed, 95% CI) | Totals not selected | |
| 11.1 Total number of patient requiring antibiotics for exacerbations | 1 | Odds Ratio (M‐H, Fixed, 95% CI) | 0.0 [0.0, 0.0] | |
| 11.2 Number of patients requiring IV antibiotics for exacerbations | 1 | Odds Ratio (M‐H, Fixed, 95% CI) | 0.0 [0.0, 0.0] | |
| 12 Exercise performance % change from baseline | 1 | Mean Difference (IV, Fixed, 95% CI) | Totals not selected | |
| 12.1 Over one week and up to two weeks | 1 | Mean Difference (IV, Fixed, 95% CI) | 0.0 [0.0, 0.0] | |
| 13 Participant satisfaction | 1 | Mean Difference (IV, Fixed, 95% CI) | Totals not selected | |
| 13.1 Over one week and up to two weeks | 1 | Mean Difference (IV, Fixed, 95% CI) | 0.0 [0.0, 0.0] |