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. 2017 May 3;2017(5):CD011986. doi: 10.1002/14651858.CD011986.pub2

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Trial Sequential Analysis for complete versus culprit‐only revascularisation on long‐term all‐cause mortality. The diversity‐adjusted required information size (DARIS) was calculated based on an expected relative risk reduction (RRR) of 20% from proportion event in control (Pc) group of 6.3% with an alpha of 2% and beta of 10%.