Comparison 2. Ketoprofen 25 mg versus placebo.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Participants with ≥ 50% pain relief over 6 hours	8	535	Risk Ratio (M‐H, Fixed, 95% CI)	4.88 [3.48, 6.85]
1.1 Dental surgery	6	452	Risk Ratio (M‐H, Fixed, 95% CI)	5.07 [3.50, 7.36]
1.2 Other surgery	2	83	Risk Ratio (M‐H, Fixed, 95% CI)	3.96 [1.77, 8.86]
2 Participants using rescue medication over 6 hours	6	402	Risk Ratio (M‐H, Fixed, 95% CI)	0.60 [0.52, 0.69]
3 Participants with any adverse event	7	490	Risk Ratio (M‐H, Fixed, 95% CI)	1.15 [0.68, 1.96]