Skip to main content
. 2017 May 4;2017(5):CD000406. doi: 10.1002/14651858.CD000406.pub5

Comparison 1. Oral calorie supplements versus no intervention or additional nutritional advice.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1.1 Change in weight (kg) 3   Mean Difference (IV, Fixed, 95% CI) Subtotals only
1.1.1 3 months 2 112 Mean Difference (IV, Fixed, 95% CI) 0.32 [‐0.09, 0.72]
1.1.2 6 months 2 117 Mean Difference (IV, Fixed, 95% CI) 0.47 [‐0.07, 1.02]
1.1.3 12 months 1 102 Mean Difference (IV, Fixed, 95% CI) 0.16 [‐0.68, 1.00]
1.2 Change in weight centile (percentile points) 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
1.2.1 3 months 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
1.2.2 6 months 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
1.2.3 12 months 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
1.3 Change in height (cm) 2   Mean Difference (IV, Fixed, 95% CI) Subtotals only
1.3.1 3 months 2 112 Mean Difference (IV, Fixed, 95% CI) ‐0.04 [‐0.36, 0.29]
1.3.2 6 months 1 101 Mean Difference (IV, Fixed, 95% CI) ‐0.47 [‐1.32, 0.38]
1.3.3 12 months 1 102 Mean Difference (IV, Fixed, 95% CI) 0.06 [‐0.50, 0.62]
1.4 Change in height centile (percentile points) 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
1.4.1 3 months 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
1.4.2 6 months 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
1.4.3 12 months 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
1.5 Change in weight for height (percentage) 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
1.5.1 3 months 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
1.6 Change in BMI (kg/m2) 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
1.6.1 3 months 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
1.6.2 6 months 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
1.6.3 12 months 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
1.7 Change in BMI centile (percentile points) 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
1.7.1 3 months 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
1.7.2 6 months 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
1.7.3 12 months 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
1.8 Change in mid‐upper arm circumference (cm) 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
1.8.1 3 months 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
1.8.2 6 months 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
1.8.3 12 months 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
1.9 Change in total Kcal/day 2   Mean Difference (IV, Fixed, 95% CI) Subtotals only
1.9.1 3 months 2 58 Mean Difference (IV, Fixed, 95% CI) 115.09 [‐121.34, 351.52]
1.9.2 6 months 1 48 Mean Difference (IV, Fixed, 95% CI) 304.86 [5.62, 604.10]
1.9.3 12 months 1 58 Mean Difference (IV, Fixed, 95% CI) 265.70 [42.94, 488.46]
1.10 Change in total protein (g)/day 2   Mean Difference (IV, Fixed, 95% CI) Subtotals only
1.10.1 3 months 2 58 Mean Difference (IV, Fixed, 95% CI) 2.51 [‐6.74, 11.77]
1.10.2 6 months 1 48 Mean Difference (IV, Fixed, 95% CI) 8.77 [‐1.24, 18.78]
1.10.3 12 months 1 58 Mean Difference (IV, Fixed, 95% CI) 6.82 [‐2.36, 16.00]
1.11 Change in total fat (g)/day 2   Mean Difference (IV, Fixed, 95% CI) Subtotals only
1.11.1 3 months 2 58 Mean Difference (IV, Fixed, 95% CI) ‐1.10 [‐15.05, 12.85]
1.11.2 6 months 1 48 Mean Difference (IV, Fixed, 95% CI) 11.74 [‐2.96, 26.44]
1.11.3 12 months 1 58 Mean Difference (IV, Fixed, 95% CI) 8.85 [‐4.64, 22.34]
1.12 Change in FEV₁ (% predicted) 2   Mean Difference (IV, Fixed, 95% CI) Subtotals only
1.12.1 3 months 2 82 Mean Difference (IV, Fixed, 95% CI) ‐7.96 [‐13.52, ‐2.40]
1.12.2 6 months 1 70 Mean Difference (IV, Fixed, 95% CI) ‐3.39 [‐9.97, 3.19]
1.12.3 12 months 1 70 Mean Difference (IV, Fixed, 95% CI) ‐1.91 [‐8.57, 4.75]
1.13 Change in FVC (% predicted) 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
1.13.1 3 months 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
1.13.2 6 months 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
1.13.3 12 months 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
1.14 Change in activity (% 24 hours) 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
1.14.1 3 months 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
1.14.2 6 months 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
1.14.3 12 months 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected