Table 6.
Laser | Aflibercept | Bevacizumab | Pegaptanib | Ranibizumab | Sham | Overall | |
SSAE | 9 | 3 | 6 | 2 | 10 | 5 | 18 |
1013 | 556 | 410 | 186 | 1303 | 528 | 4229 | |
ATC* | 10 | 3 | 4 | 2 | 8 | 2 | 15 |
824 | 846 | 330 | 188 | 1113 | 184 | 3718 | |
Death | 11 | 3 | 4 | 2 | 10 | 3 | 17 |
903 | 846 | 333 | 188 | 1521 | 434 | 4455 |
For each safety outcome, numbers in the table are the total number of studies (upper line for each outcome) and the total number of eyes (lower line for each outcome), as available by treatment and measured at the longest available follow‐up.
(*) combined incidence of (1) cardiovascular, hemorrhagic, and unknown death; (2) nonfatal MI; and (3) nonfatal stroke.