Moore 2015.
Methods | RCT Mobility CCT vs home stretching (matched duration) |
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Participants | 40 participants (intervention = 20, comparison = 20), mean time since stroke 1.5 years, mean age 69 years, able to complete 6mWT with or without gait aid | |
Interventions | Intervention: mobility CCT based on FAME programme including warm‐up, stretching, functional strengthening, balance, agility & fitness, cool down; 45‐60 minutes, 3 times/week for 19 weeks Comparison: home stretching programme of matched duration; 45 to 60 minutes 3 times/week for 19 weeks Staff:participant ratio: not reported |
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Outcomes | 6mWT, gait speed, BBS, SIS (physical), VO2 peak, peak work rate, Addenbrook's Cognitive Examination (revised, ACE‐r), blood cholesterol, 2‐hour glucose, HOMA index, blood pressure, BMI, fat mass, brain physiology (cerebral blood flow) | |
Notes | Adverse events reported, not actual therapy time delivered | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Low risk | "A computerized random number generator was used to allocate treatment by an independent administrator after screening." |
Allocation concealment (selection bias) | Low risk | "… the administrator was telephoned for the next number in the sequence to enable participant randomisation." |
Blinding (performance bias and detection bias) All outcomes | Low risk | Single‐blind RCT No mention of blinding participants or personnel. It would be unlikely that study participants and staff were blinded due to the nature of the trial. Unlikely to influence outcomes Assessors were blinded |
Incomplete outcome data (attrition bias) All outcomes | Low risk | States participants performed "… > 90% of outcome assessments and exercise sessions." Although these were not defined All participants completed the intervention, none lost to follow‐up |
Selective reporting (reporting bias) | Unclear risk | No protocol available |
Other bias | Low risk | No other sources of bias evident |