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. 2017 May 11;2017(5):CD001159. doi: 10.1002/14651858.CD001159.pub2

Comparison 1. Nerve block versus other modes of analgesia.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Pain on movement within 30 minutes of block placement 8 373 Std. Mean Difference (Random, 95% CI) ‐1.41 [‐2.14, ‐0.67]
2 Pain at rest within 30 minutes after block placement 7 322 Std. Mean Difference (Random, 95% CI) ‐0.80 [‐1.25, ‐0.35]
3 Pain at rest at 6 to 8 hours after surgery 5 286 Mean Difference (IV, Random, 95% CI) ‐0.38 [‐0.70, ‐0.06]
4 Pain on movement at 24 hours after surgery 4 195 Mean Difference (IV, Random, 95% CI) ‐0.39 [‐1.08, 0.30]
4.1 Surgical technique unspecified 3 169 Mean Difference (IV, Random, 95% CI) 0.09 [‐0.10, 0.29]
4.2 Arthroplasty for 38.4% of participants 1 26 Mean Difference (IV, Random, 95% CI) ‐1.94 [‐2.75, ‐1.13]
5 Pain at rest at 24 hours after surgery 8 435 Mean Difference (IV, Random, 95% CI) ‐0.68 [‐1.23, ‐0.13]
5.1 Single shot blocks 2 80 Mean Difference (IV, Random, 95% CI) ‐0.5 [‐0.90, ‐0.10]
5.2 Continuous blocks 6 355 Mean Difference (IV, Random, 95% CI) ‐0.78 [‐1.58, 0.03]
6 Pain on movement at 48 hours 2 129 Mean Difference (IV, Fixed, 95% CI) 0.09 [‐0.23, 0.40]
7 Pain at rest at 48 hours after surgery 5 335 Mean Difference (IV, Random, 95% CI) ‐0.37 [‐0.87, 0.13]
7.1 Psoas compartment block 1 40 Mean Difference (IV, Random, 95% CI) ‐1.10 [‐2.26, 0.06]
7.2 Femoral nerve block 3 191 Mean Difference (IV, Random, 95% CI) 0.06 [‐0.16, 0.28]
7.3 Fascia iliaca block 1 104 Mean Difference (IV, Random, 95% CI) ‐0.92 [‐1.47, ‐0.36]
8 Pain at rest at 72 hours after surgery 2 140 Mean Difference (IV, Random, 95% CI) ‐0.48 [‐1.83, 0.87]
8.1 Psoas compartment block 1 40 Mean Difference (IV, Random, 95% CI) ‐1.20 [‐1.77, ‐0.63]
8.2 Femoral nerve block 1 100 Mean Difference (IV, Random, 95% CI) 0.18 [0.03, 0.33]
9 Acute confusional state 7 676 Risk Ratio (M‐H, Random, 95% CI) 0.69 [0.38, 1.27]
9.1 Peripheral nerve block based on landmarks 4 501 Risk Ratio (M‐H, Random, 95% CI) 0.82 [0.23, 2.93]
9.2 Peripheral nerve block based on nerve stimulator 3 175 Risk Ratio (M‐H, Random, 95% CI) 0.56 [0.32, 0.98]
10 Pneumonia 3 131 Risk Ratio (M‐H, Fixed, 95% CI) 0.41 [0.19, 0.89]
11 Mortality 7 316 Risk Ratio (M‐H, Fixed, 95% CI) 0.72 [0.34, 1.52]
12 Time to first mobilization 2 155 Mean Difference (IV, Random, 95% CI) ‐11.25 [‐14.34, ‐8.15]
13 Costs of analgesic regimens 2   Std. Mean Difference (Random, 95% CI) Subtotals only
13.1 Single shot blocks 1 75 Std. Mean Difference (Random, 95% CI) ‐3.48 [‐4.23, ‐2.74]
13.2 Continuous blocks 1 62 Std. Mean Difference (Random, 95% CI) 0.93 [0.37, 1.48]
14 Pressure sores 3 187 Risk Ratio (M‐H, Random, 95% CI) 0.47 [0.09, 2.53]
14.1 Single shot femoral nerve block (on admission) 2 125 Risk Ratio (M‐H, Random, 95% CI) 0.18 [0.02, 1.38]
14.2 Continous femoral nerve block (after surgery) 1 62 Risk Ratio (M‐H, Random, 95% CI) 0.98 [0.19, 4.90]
15 Opioid requirement 7 285 Std. Mean Difference (Random, 95% CI) ‐0.70 [‐0.96, ‐0.44]
15.1 Single shot blocks 5 245 Std. Mean Difference (Random, 95% CI) ‐0.73 [‐1.01, ‐0.44]
15.2 Continuous blocks 2 40 Std. Mean Difference (Random, 95% CI) ‐0.55 [‐1.18, 0.08]
16 Participant satisfaction 5 237 Std. Mean Difference (Random, 95% CI) 0.91 [0.62, 1.20]