Jones 1985.
Methods | RCT Informed consents obtained Setting: United Kingdom Funding: unspecified |
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Participants | Orthopaedic hospital in London, UK
19 participants with an extracapsular hip fracture treated with a pin and plate or a sliding hip screw
Mean age: 82 years (range 67‐93)
Percentage female: 95%
Lost to follow‐up: none Excluded: other painful lesions, signs of moderate or severe dementia, < 65 years of age, systemic disease indicating an alternative method of anaesthesia (e.g. spinal) |
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Interventions |
Tretament group: lateral cutaneous nerve of thigh block with 15 mL 0.5% bupivacaine and adrenaline (n = 10)
Control group: no block (control) (n = 9) All participants had general anaesthesia with fentanyl, thiopentone, suxamethonium, nitrous oxide, halothane. Blocks performed at completion of surgery |
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Outcomes | Death (24 hours) | |
Notes | One participant died within 24 hours of surgery, and results for this participant were not given Length of follow‐up: not stated |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Low risk | 'Random envelopes' |
Allocation concealment (selection bias) | Low risk | 'Random envelopes' opened at completion of surgery |
Blinding of participants and personnel (performance bias) All outcomes | Unclear risk | Not mentioned |
Blinding of outcome assessment (detection bias) All outcomes | Low risk | Postoperative analgesia was prescribed before allocation to respective groups, with administration performed at the discretion of the nursing staff, who were unaware of whether a block had been performed. The dose of pethidine was 25 or 50 mg intramuscularly, depending on the participant's estimated weight ‐ not on general condition |
Incomplete outcome data (attrition bias) All outcomes | Low risk | One lost to follow‐up Results for 1 participant who died are not included: "One patient in Group 2 who died within the 24‐hour period is not included in analysis of the results: there are thus nine patients in each group" |
Selective reporting (reporting bias) | Low risk | All measurements mentioned in methods section given in results section |
Other bias | Low risk | Groups well balanced |