Kullenberg 2004.
Methods | RCT Setting: Sweden Funding: no conflict of interest declared, classified as departmental resources |
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Participants | Orthopaedic hospital in Sweden
80 participants with a hip fracture
Mean age: 82 years (range not stated)
Percentage female: 64%
Lost to follow‐up: not stated Excluded: inability to rate their pain |
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Interventions |
Treatment group: femoral nerve block inserted at the time of admission with 30 mL ropivacaine (7.5 mg/mL) (n = 40). Mean bock duration 15.8 ± 5.6 hours. Four participants had their block during transportation to the hospital. The block was repeated for 3 participants owing to a long delay before surgery (23.9 hours, 26.3 hours and 30.9 hours) Control group: no injection (n = 40) |
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Outcomes | Confusion (Pfeiffer test, graded according to a 4‐degree scale (0‐3: no, light, moderate and pronounced confusion) at 48 hours Time to first mobilization Pressure sores Opioids used per 24 hours |
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Notes | Length of follow‐up: length of acute hospital stay (mean 11 days) No complication related to the nerve block All participants indicated that they would consider a new future blockade if this would be necessary |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Low risk | Use of sealed envelopes |
Allocation concealment (selection bias) | Low risk | Use of sealed envelopes |
Blinding of participants and personnel (performance bias) All outcomes | Unclear risk | Not mentioned |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | Not mentioned |
Incomplete outcome data (attrition bias) All outcomes | Low risk | None lost to follow‐up Five failed blocks; participants kept in their treatment groups |
Selective reporting (reporting bias) | Low risk | All measurements mentioned in methods section given in results section |
Other bias | Unclear risk | Groups well balanced except for a longer delay in arrival to surgery for the block group (15.5 hours vs 5.8 hours) |