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. 2017 May 11;2017(5):CD001159. doi: 10.1002/14651858.CD001159.pub2

NCT01219088.

Trial name or title Postoperative pain control among intrathecal 0.1 mg morphine, femoral nerve block or periarticular infiltration of 20 mL of 0.25% bupivacaine in patients post intramedullary hip screw
Methods Parallel RCT
Single‐blind (outcome assessor)
Participants Inclusion criteria: 18‐90 years old, good consciousness, well co‐operated, can use patient‐controlled analgesia machine, ASA physical status I‐III, no contraindication for spinal anaesthesia, accept spinal anaesthesia, body weight > 30 kg, body mass index 20‐35 kg/m2, no history of research drug allergy
Exclusion criteria: previous history of hip surgery (the same side), pathological fracture, severe infection or bone cancer
Interventions Treatment group 1: femoral nerve block, spinal anaesthesia plus femoral nerve block with 20 mL of 0.25% bupivacaine
Treatment group 2: periarticular bupivacaine infiltration, spinal anaesthesia plus periarticular infiltration with 20 mL of 0.25% bupivacaine
Control group 1: spinal anaesthesia with 0.5% bupivacaine alone
Control group 2: spinal anaesthesia plus 0.1 mg of intrathecal morphine
Outcomes Primary outcome measures: amount of morphine consumed during first 24 hours after surgery
 Secondary outcome measures: efficacy of pain control, patient satisfaction, incidences of adverse events (nausea, vomiting, pruritus)
Starting date September 2010
Contact information Thitima Chinachoti, MD (Madihol University), Faculty of Medicine Siniraj Hospital, Bangok, Thailand, 10700
Notes