Summary of findings for the main comparison. CHM versus antibiotics for women with recurrent UTI.
CHM versus antibiotics for women with recurrent UTI | ||||||
Patient or population: women with recurrent UTI Settings: China Intervention: CHM Comparison: antibiotics | ||||||
Outcomes | Illustrative comparative risks* (95% CI) | Relative effect (95% CI) | No of participants (studies) | Quality of the evidence (GRADE) | Comments | |
Assumed risk | Corresponding risk | |||||
Antibiotics | CHM | |||||
Effectiveness | Study population | RR 1.24 (1.13 to 1.37) | 282 (3) | ⊕⊝⊝⊝ very low | ||
764 per 1000 | 948 per 1000 (864 to 1000) | |||||
Moderate | ||||||
769 per 1000 | 954 per 1000 (869 to 1000) | |||||
Recurrence Follow‐up: mean 5 months | Study population | RR 0.28 (0.09 to 0.82) | 282 (3) | ⊕⊝⊝⊝ very low | ||
550 per 1000 | 154 per 1000 (50 to 451) | |||||
Moderate | ||||||
712 per 1000 | 199 per 1000 (64 to 584) | |||||
*The basis for the assumed risk (e.g. the median control group risk across studies) is provided in footnotes. The corresponding risk (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI). CI: Confidence interval; RR: Risk ratio | ||||||
GRADE Working Group grades of evidence High quality: Further research is very unlikely to change our confidence in the estimate of effect. Moderate quality: Further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate. Low quality: Further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate. Very low quality: We are very uncertain about the estimate. |
CHM ‐ Chinese herbal medicine; UTI ‐ urinary tract infection