Mendonca 2016.
Methods | 3 groups: aerobic exercise training and active transcranial direct current stimulation (tDCS) intervention; aerobic exercise and placebo tDCS; placebo AE and tDCS Length: 8 weeks; follow‐up conducted 1 month (T3) and 2 months (T4) after the end of the intervention period Study design: randomized clinical trial with parallel groups |
Participants | Female:Male: 44:1 Age (years (SD)): 44.5 (14), 48 (11.8), 49.9 (10.6) Inclusion: completed high school and age between 18 and 65 years Exclusion: on medication for pain control for less than 2 months; had been treated for depression for less than 2 months; had epilepsy, psychiatric disorder, or any recent episode of neurological disorder, such as idiopathic syncope; pregnant and infant‐aged; had metallic implants in the brain; using illicit drugs; had been undergoing some type of physical treatment for less than 2 months Duration of illness (years (SD)): proxy ‐ pain duration (months (SD)): 140.6 (72.2); 149.3 (111.1); 125.6 (100.2) |
Interventions | Participants were divided into 3 intervention groups: tDCS/AE, which received active intervention of aerobic exercise training and active tDCS intervention; AE, which received active intervention of aerobic exercise and placebo tDCS; and tDCS, which received placebo AE and active intervention for tDCS |
Outcomes | Intensity of pain, level of anxiety, quality of life, mood, pressure pain threshold, and cortical plasticity, as indexed by transcranial magnetic stimulation. All variables were measured 1 week before the beginning of the intervention (baseline), after the intervention period (T2), and during periods of follow‐up conducted 1 month (T3) and 2 months (T4) after the end of the intervention period |
Notes | Country: Brazil Language: English Study author contacted: not yet Funding source/declaration of interest: not assessed yet Trial registry: not assessed yet |