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. 2017 Jun 21;2017(6):CD012700. doi: 10.1002/14651858.CD012700

Sanudo 2015.

Methods 2 groups: aerobic exercise (AE); usual care control
Length: 24 weeks
Study design: randomized clinical trial with parallel groups
Participants Female:Male: 28:0
Age (years (SE)): 58 (2); 55 (2)
Inclusion: diagnosis of fibromyalgia according to ACR guidelines
Exclusion: pulmonary, cardiovascular, severe psychiatric, or inflammatory rheumatic disease. In addition, those who attended to psychological or physical therapy, or received exercise training, over the past year
Duration of illness (years (SD)): not assessed
Interventions Aerobic exercise (n = 16): 2 aerobic exercise sessions per week of 45–60 minutes' duration including 15–20 minutes of steady state aerobic exercise at 60% to 65% of predicted maximum heart rate (HRmax) and 15 minutes of interval training at 75%‐80% HRmax (6 repetitions of 1.5 minutes, with 1 minute interpolated rest intervals)
Usual care (n = 12)
Outcomes Cardiac autonomic modulation (power spectral analysis of HRV). Symptom severity (pain VAS), sleep disturbance, stiffness, anxiety, and depression
Notes Country: Spain
Language: English
Study author contacted: not yet
Funding: University of Seville provided support for this study

ACR: American College of Rheumatology; AE: aerobic exercise; ASES: Arthritis self‐efficacy scale; BDI: Beck Depression Inventory; BE: bout of exercise; CSF: cerebrospinal fluid; FIQ: Fibromyalgia Impact Questionnaire; FM: fibromyalgia; HRmax: maximum heart rate; HRQL: health‐related quality of life; HRV: heart rate variability; IGF‐1: insulin growth factor‐1; LIW: low‐intensity walking; MMP‐3: matrix metalloproteinase 3; NW: Nordic walking; RBP: resting blood pressure; SD: standard deviation; tDCS: transcranial direct current stimulation; TIBS: Tetraks interactive balance system; TUG: Timed Up‐Go; VAS: visual analogue scale