|
Trial |
Experimental intervention |
Type and number of participants with a serious adverse events (Experimental group) |
Proportion of participants with a serious adverse event (Experimental group) |
Type and number of participants with a serious adverse events (Control group) |
Proportion of participants with a serious adverse event (Control group) |
| Bellantone 1988 |
Parenteral nutrition |
1 sepsis |
1 out of 54 |
10 sepsis |
10 out of 46 |
| Bozzetti 2000 |
Parenteral nutrition |
1 anastomotic leak, 3 respiratory infections, 2 respiratory insufficiency |
6 out of 43 |
2 anastomotic leaks, 1 renal failure, 2 abdominal abscesses, 4 respiratory infections, 3 respiratory insufficieny |
12 out of 47 |
| Brennan 1994 |
Parenteral nutrition |
7 anastomotic leaks, 5 pneumonias, 1 GI haemorrhages, 8 GI fistula, 4 ileus, 2 myocardial infarction, 12 abscess, 4 deep infection, 7 peritonitis |
50 out of 60 |
3 anastomotic leaks, 6 pneumonias, 1 pulmonary embolism, 2 GI haemorrhages, 5 GI fistula, 1 myocardial infarction, 2 abscess, 4 deep infection, 2 peritonitis |
26 out of 57 |
| Chen 1995a |
Enteral nutrition |
no serious adverse events reported |
0 out of 16 |
1 anastomotic leak |
1 out of 8 |
| Chen 2000a |
Enteral nutrition |
1 anastomotic leak |
1 out of 10 |
no serious adverse events reported |
0 out of 10 |
| Chen 2006 |
Enteral nutrition |
no serious adverse events reported |
0 out of 21 |
1 septic complication |
1 out of 20 |
| Dennis 2005 |
Oral nutrition |
50 strokes, 23 pulmonary embolisms, 43 DVTs, 28 GI haemorrhages, 28 ACS' |
172 out of 2012 |
43 strokes, 18 pulmonary embolism, 29 DVTs, 18 GI haemorrhage, 22 ACS |
130 out of 2000 |
| Dennis 2006 |
Enteral nutrition |
15 strokes, 6 pulmonary embolisms, 11 DVTs, 22 GI haemorrhages, 7 ACS' |
61 out of 429 |
23 strokes, 8 pulmonary embolisms, 13 DVTs, 11 GI haemorrhages, 13 ACS' |
68 out of 428 |
| Doglietto 1990 |
Parenteral nutrition |
3 sepsis |
3 out of 9 |
7 sepsis |
7 out of 12 |
| Doglietto 1996 |
Oral nutrition |
20 anastomotic leaks, 14 pneumonias, 2 pulmonary embolisms, 2 renal failure, 6 abdominal abscess, 3 unspecific infection, 10 wound dehiscences, 1 pulmonary failure, 11 gastrointestinal complications, 6 cardiovascular complications, 4 haemoperitoneum |
79 out of 338 |
18 anastomotic leaks, 9 pneumonias, 1 pulmonary embolisms, 3 renal failure, 1 abdominal abscess, 2 unspecific infection, 3 wound dehiscences, 2 pulmonary failure, 6 bacteraemia, 23 gastrointestinal complications, 6 cardiovascular complications, 5 haemoperitoneum |
79 out of 340 |
| Ding 2009 |
Parenteral nutrition |
1 respiratory infection |
1 out of 21 |
2 respiratory infection |
2 out of 21 |
| Dong 1996 |
Enteral nutrition |
no serious adverse events reported |
0 out of 256 |
6 anastomotic leaks |
6 out of 264 |
| Fan 1994 |
Parenteral nutrition |
4 GI haemorrhages, 4 GI fistulas, 4 hepatic comas |
12 out of 64 |
1 GI haemorrhages, 5 GI fistulas, 4 hepatic comas |
10 out of 60 |
| Hartgrink 1998 |
Enteral nutrition |
25 pressure sores |
25 out of 48 |
30 pressure sores |
30 out of 53 |
| Hoffmann 1988 |
Enteral nutrition |
no serious adverse events reported |
0 out of 43 |
3 anastomotic leaks, 2 myocardial infarction |
5 out of 16 |
| Ji 1999 |
Enteral nutrition |
2 abdominal abscess |
2 out of 20 |
no serious adverse events reported |
0 out of 10 |
| Johansen 2004 |
General nutrition |
4 pneumonia, 1 DVTs, 4 sepsis, 2 empyemas, 0 gastroenteritis, 1 GI complications, |
12 out of 108 |
4 pneumonia, 1 stroke, 2 sepsis, 1 gastroenteritis, 2 GI complications |
10 out of 104 |
| Kearns 1992 |
Enteral nutrition |
2 renal failures |
2 out of 16 |
2 renal failures |
2 out of 15 |
| Keele 1997 |
Oral nutrition |
no serious adverse events reported |
0 out of 43 |
1 GI perforation |
1 out of 43 |
| Larsson 1990a |
Oral nutrition |
20 pressure sores |
20 out of 197 |
29 pressure sores |
29 out of 328 |
| Ledinghen 1997 |
Enteral nutrition |
4 variceal bleedings, 1 peritonitis |
5 out of 12 |
1 peritonitis |
1 out of 10 |
| Liu 1996 |
Parenteral nutrition |
no serious adverse events reported |
0 out of 14 |
1 anastomotic leak, 1 GI fistula |
2 out of 15 |
| Malhotra 2004 |
Enteral nutrition |
21 Pneumonia, Wound infection 27, Wound dehiscence 4, anastomotic Leak 7, Septicaemia 20 |
27 out of 98 |
Pneumonia 30, Wound infection 31, Wound dehiscence 9, Leak 13, Septicaemia 30. |
31 out of 97 |
| Maude 2011 |
Enteral nutrition |
8 sepsis |
8 out of 27 |
7 sepsis |
7 out of 29 |
| Neuvonen 1984 |
Parenteral nutrition |
no serious adverse events reported |
0 out of 9 |
1 sepsis |
1 out of 12 |
| Page 2002 |
Enteral nutrition |
no serious adverse events reported |
0 out of 20 |
1 pulmonary embolism |
1 out of 20 |
| Pupelis 2000 |
Enteral nutrition |
2 peritonitis |
2 out of 11 |
5 peritonitis |
5 out of 18 |
| Pupelis 2001 |
Enteral nutrition |
no serious adverse events reported |
0 out of 30 |
4 GI fistulas |
4 out of 30 |
| Reissman 1995 |
Oral nutrition |
no serious adverse events reported |
0 out of 80 |
1 anastomotic leak |
1 out of 81 |
| Rimbau 1989 |
Parenteral nutrition |
1 pneumonia |
1 out of 10 |
2 pneumonias |
2 out of 10 |
| Sabin 1998 |
Parenteral nutrition |
2 pneumoperitoneum's |
2 out of 40 |
2 anastomotic leaks, 2 pneumoperitoneum's |
4 out of 40 |
| Samuels 1981 |
Parenteral nutrition |
2 pneumonias, 5 sepsis |
7 out of 16 |
2 sepsis |
2 out of 14 |
| Schroeder 1991 |
Enteral nutrition |
1 myocardial infarction |
1 out of 16 |
1 myocardial infarction |
1 out of 16 |
| Simon 1988 |
Parenteral nutrition |
no serious adverse events reported |
0 out of 15 |
2 hepatic encephalopathies |
2 out of 17 |
| Smith 1988 |
Parenteral nutrition |
no serious adverse events reported |
0 out of 17 |
2 respiratory infection |
2 out of 17 |
| Starke 2011 |
General nutrition |
no serious adverse events reported |
0 out of 66 |
1 stroke, 1 DVT, 1 septic arthritis, 2 myocardial infarction |
5 out of 66 |
| Thompson 1981 |
Parenteral nutrition |
1 empyema, 1 pelvic abscess |
2 out of 12 |
1 intraabdominal abscess |
1 out of 9 |
| Tong 2006a |
Mixed nutrition |
1 hepatic encephalopathy |
1 out of 90 |
4 anastomotic leak, 5 hepatic encephalopathies |
9 out of 36 |
| Vicic 2013 |
Enteral nutrition |
2 sepsis, 2 multi organ failure, |
4 out of 52 |
6 sepsis, 3 multi organ failure |
9 out of 49 |
| Watters 1997 |
Enteral nutrition |
1 anastomotic leak |
1 out of 13 |
3 anastomotic leaks |
3 out of 15 |
| Wu 2007a |
Mixed nutrition |
11 anastomotic leaks, 6 DVT, 15 sepsis |
32 out of 430 |
10 anastomotic leaks, 15 sepsis |
25 out of 216 |
| Yamada 1983 |
Parenteral nutrition |
1 wound dehiscence |
1 out of 18 |
1 anastomotic leak, 2 pneumonias, 1 sepsis, 1 ileus |
5 out of 16 |
| Zhang 2013 |
Enteral nutrition |
2 GI haemorrhage |
2 out of 50 |
4 GI haemorrhage |
4 out of 50 |
