Chen 1995a.
Methods | Randomised clinical trial, China | |
Participants | 24 hospitalised adults undergoing abdominal elective surgery, at nutritional risk due to major surgery Male:Female = 15:9 Mean age = 53.5 years Exclusion criteria: Unclear |
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Interventions | Experimental group A: Recieved the compound nutrition elements of Qingdao biochemical pharmaceutical factory ( 400 kcal, N 2.56 g per 100 g) from the 1st day after the operation. It was infused as a 10% nutrient solution continuously with the speed of 50 ml/hr, reaching the maximum volume (25% of the daily nutrient solution 3000 ml) gradually within a few days according to tolerance. Oral intake was maintained during this time. The amount of perfusion was gradually decreased and the tube removed, when nutrition sufficed from oral intake. (n = 8) Experimental group B: enteral nutrition support after postoperative flatus, in the same way as experimental group A. (n = 8) Control group: Conventional i.v. infusion after surgery. Some received albumin or blood transfusion once or twice. (n = 8) |
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Outcomes | Complication, weight, daily calorie, nitrogen and liquid intake, albumin and transferrin, urea nitrogen concentration | |
Study dates | Not stated | |
Notes | We tried but failed to contact the author by phone. | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | The trial was described as being randomised, but it was unclear how the sequence was generated. |
Allocation concealment (selection bias) | Unclear risk | The trial was described as being randomised, but it was unclear how the allocation was concealed. |
Blinding of participants and personnel (performance bias) All outcomes | High risk | Participants and personnel were not blinded. |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | The procedure of blinding was insufficiently described. |
Incomplete outcome data (attrition bias) All outcomes | Unclear risk | The numbers and reasons for withdrawals and dropouts were not clearly stated. |
Selective reporting (reporting bias) | Unclear risk | No protocol could be obtained and the trial did not report on all‐cause mortality. |
For‐profit bias | Unclear risk | It was unclear how the trial was funded. |
Other bias | Low risk | The trial appeared to be free of other components that could put it at risk of bias. |