Chen 2000b.
Methods | Randomised clinical trial, China | |
Participants | 30 hospitalised adults undergoing moderate or more elective abdominal surgery, at nutritional risk due to abdominal surgery Male:Female = 17:13 Exclusion criteria: Metabolic and infectious diseases, having taken steroids or immunosuppressive agents or both recently |
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Interventions | Experimental group A: Enteral nutrition, Nutrison (product of Holland Nutricia company) were infused through a nutrition tube in upper jejunum on the 1st postoperative day, 1/3 of the total amount on the 1st day, 2/3 on the 2nd day, and full amount (125.4 KJ‐1·kg‐1·d‐1) on the 3rd day(n = 10) Experimental group B: Parenteral nutrition (Huarui company products) through peripheral or central vein from the 1st postoperative day, with the same usage of enteral nutrition group(n = 10) Control group: Conventional infusion for 8 days, the average calorie intake was about 2514 KJ·d‐1(n = 10) |
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Outcomes | Complications, plasma protein (total protein, albumin and transferrin), CD3, CD4, CD8, D4/CD8. | |
Study dates | Not stated | |
Notes | Same trial as Chen 2000a. We tried but failed to contact the author by phone (0543‐3258597). | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | The trial was described as being randomised, but it was unclear how the sequence was generated. |
Allocation concealment (selection bias) | Unclear risk | The trial was described as being randomised, but it was unclear how the allocation was concealed. |
Blinding of participants and personnel (performance bias) All outcomes | High risk | Participants and personnel were not blinded. |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | The procedure of blinding was insufficiently described. |
Incomplete outcome data (attrition bias) All outcomes | Unclear risk | The numbers and reasons for withdrawals and dropouts were not clearly stated. |
Selective reporting (reporting bias) | Unclear risk | No protocol could be obtained and the trial did not report on all‐cause mortality. |
For‐profit bias | Unclear risk | It was unclear how the trial was funded. |
Other bias | Low risk | The trial appeared to be free of other components that could put it at risk of bias. |