Dong 1996.
Methods | Randomised clinical trial, China | |
Participants | 520 hospitalised adults undergoing oesophageal and gastric resection, at nutritional risk due to major surgery Male:Female = 340:180 Mean age = 56.5 years Exclusion criteria: None stated |
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Interventions | Experimental group: Received enteral nutrition in the form of mixed milk post‐surgery On the first day,1000 ml mixed milk was given. If no side effect occurred, a minimum of 2500 ml a day were given from the 2nd day, up to 4 ‐ 6 times a day, at a speed of 30 ml per min. After 7 ‐ 9 days the nutrition tube was removed , if there were no serious adverse effects.(n = 256) Control group: No intervention(n = 264) Co‐interventions: Post‐surgery a daily supplement of glucose 150 ˜ 200 g was given, as well as a discontinuous transmission of plasma, blood or albumin, to maintain the water and electrolyte balance. This was continued until the oral intake was started again. |
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Outcomes | Albumin, pre‐albumin, transferrin, weight difference, nitrogen balance | |
Study dates | Not stated | |
Notes | We could find no contact information for the author. | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Not described |
Allocation concealment (selection bias) | Unclear risk | Not described |
Blinding of participants and personnel (performance bias) All outcomes | High risk | Participants and personnel were not blinded |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | Not described |
Incomplete outcome data (attrition bias) All outcomes | Unclear risk | The number of participants with incomplete data was not reproted |
Selective reporting (reporting bias) | Unclear risk | No protocol could be obtained and the trial did not report all‐cause mortality or serious adverse events. |
For‐profit bias | Unclear risk | It was unclear how the trial was funded |
Other bias | Low risk | The trial appeared to be free of other components that could put it at risk of bias.Other bias |