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. 2017 May 19;2017(5):CD011598. doi: 10.1002/14651858.CD011598.pub2

Eneroth 2005.

Methods Randomised clinical trial, Sweden
Participants 80 hospitalised adults admitted for hip surgery, at nutritional risk because of being frail elderly with minor surgery
Male:Female = 17:63
Mean age = 81.5 years
Exclusion criteria: Multiple fractures, pathologic fractures, malignant disease, inflammatory joint disease, pain or functional impairment other than the hip fracture which might hamper normal mobilisation, depression, dementia, acute psychosis, known alcohol or medication abuse, epileptic seizures, diseases of such severity that they might negatively influenced the supplementary treatment regimen
Interventions Experimental group: intravenous supplementary nutrition (1000 kcal/day) for 3 days followed by OSN (400 kcal/day) for 7 days or until discharge(n = 40)
 Control group: No intervention(n = 40)
Co‐interventions: Standard hospital food and beverage
Outcomes Anthropometrics (triceps skin‐fold, arm muscle circumference, BMI), biochemistry, SGA‐screening
Study dates Not stated
Notes We contacted the authors on 12th November 2015 by email: magnus.eneroth@med.lu.se. We received a reply (allocation concealment).
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk The trial was described as being randomised, but it was unclear how the sequence was generated.
Allocation concealment (selection bias) Low risk The trial used sealed, opaque envelopes for allocation concealment.
Blinding of participants and personnel (performance bias) 
 All outcomes High risk The trial was described as being unblinded.
Blinding of outcome assessment (detection bias) 
 All outcomes High risk The trial was described as being unblinded.
Incomplete outcome data (attrition bias) 
 All outcomes High risk There were above 5% dropouts on BMI, and it was unclear who and how these were handled.
Selective reporting (reporting bias) Low risk No protocol could be obtained. The trial reported mortality and complications.
For‐profit bias Low risk This trial was supported by a non‐profit organisation (Medical Faculty of Lund University, the County of Skane and the Swedish National Board of Health and Welfare).
Other bias Low risk The trial appeared to be free of other components that could put it at risk of bias.