Heim 1985.
Methods | Randomised clinical trial, Germany | |
Participants | 36 hospitalised adults with advanced colorectal carcinoma, at nutritional risk due to trialist indication Male:Female = 20:16 Mean age = 52 years Exclusion criteria: None stated |
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Interventions | Experimental group: a standard 10% amino acid solution, 40% dextrose and 10% fat solution over a 10‐day period(n = 18) Control group: No intervention(n = 18) Co‐intervention: chemotherapy |
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Outcomes | Survival (not usable), side effects of parenteral nutrition | |
Study dates | Not stated | |
Notes | We could obtain no contact information for the authors. | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Not described |
Allocation concealment (selection bias) | Unclear risk | Not described |
Blinding of participants and personnel (performance bias) All outcomes | Unclear risk | Not described |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | Not described |
Incomplete outcome data (attrition bias) All outcomes | Unclear risk | The number of participants with incomplete data was not reported. |
Selective reporting (reporting bias) | Low risk | The trial reported survival and side effects. |
For‐profit bias | Unclear risk | It was unclear how the trial was funded. |
Other bias | Low risk | The trial appeared to be free of other components that could put it at risk of bias. |