Henriksen 2003a.

Methods	Randomised clinical trial, Denmark
Participants	58 hospitalised adults admitted for bowel resection, at nutritional risk due to major surgery Male:Female = 21:37 Mean age = 63.7 years Exclusion criteria: inflammatory bowel disease, disseminated malignant disease, previous treatment for intra‐abdominal cancer, serious cardiovascular disease (New York Heart Association angina class III and IV) diabetes mellitus, disabling mental disease, dementia or a history of alcoholic, medicine or drug abuse
Interventions	The night before surgery: Experimental group 1: 12.5 g/100 ml carbohydrate (maltodextrin) drink (n = 16) Experimental group 2: 2.5 g/100 ml carbohydrate (maltodextrin) and 3.5 g/100 ml of hydrolyzed soy protein (n = 16) Control group: No treatment (n = 8) Co‐interventions: Pure water until 3 hrs before induction of anaesthesia + basic postoperative regimen
Outcomes	Voluntary grip and quadriceps strength, body composition, pulmonary function, VAS‐score of 8 parameters of well‐being, muscle biopsies and insulin, glucagon, IGF‐1 and free fatty acids
Study dates	Not stated
Notes	We contacted the authors on 19th August 2015 by email: gaarden@dadlnet.dk . We received a reply.
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Not described
Allocation concealment (selection bias)	Unclear risk	The trial used sealed envelopes for allocation but it was unclear if they were opaque.
Blinding of participants and personnel (performance bias) All outcomes	Unclear risk	Not described
Blinding of outcome assessment (detection bias) All outcomes	Unclear risk	Nutritional status was described as blinded, but it was unclear how the rest of the outcomes were assessed.
Incomplete outcome data (attrition bias) All outcomes	Unclear risk	The number of dropouts exceeds 5%. The dropouts were described, but it was unclear from which group they came.
Selective reporting (reporting bias)	Unclear risk	No protocol could be obtained, and the trial did not report all‐cause mortality or serious adverse events.
For‐profit bias	Unclear risk	It was unclear how the trial was funded.
Other bias	Low risk	The trial appeared to be free of other components that could put it at risk of bias.