Herndon 1987.
Methods | Randomised clinical trial, USA | |
Participants | 28 hospitalised adults with burns > 50% of total body surface area, at nutritional risk due to trauma Mean age = 36 years |
|
Interventions | Experimental group: supplementary TPN (n = 13)
Control group: No intervention (n = 15) Co‐interventions: peripheral intravenous fluids to meet fluid requirements |
|
Outcomes | Caloric intake, immune function, liver function, serum albumin, mortality | |
Study dates | Not stated | |
Notes | We contacted the authors on 19th August 2015 by email: dherndon@utmb.edu. We received no reply. | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Not described |
Allocation concealment (selection bias) | Unclear risk | Not described |
Blinding of participants and personnel (performance bias) All outcomes | Unclear risk | Not described |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | Not described |
Incomplete outcome data (attrition bias) All outcomes | Unclear risk | The number of participants with incomplete data was not reported. |
Selective reporting (reporting bias) | Unclear risk | No protocol could be obtained, and the trial did not report all‐cause mortality or serious adverse events. |
For‐profit bias | Unclear risk | It was unclear how the trial was funded. |
Other bias | Low risk | The trial appeared to be free of other components that could put it at risk of bias. |