Skip to main content
. 2017 May 19;2017(5):CD011598. doi: 10.1002/14651858.CD011598.pub2

Herndon 1987.

Methods Randomised clinical trial, USA
Participants 28 hospitalised adults with burns > 50% of total body surface area, at nutritional risk due to trauma
Mean age = 36 years
Interventions Experimental group: supplementary TPN (n = 13)
 Control group: No intervention (n = 15)
Co‐interventions: peripheral intravenous fluids to meet fluid requirements
Outcomes Caloric intake, immune function, liver function, serum albumin, mortality
Study dates Not stated
Notes We contacted the authors on 19th August 2015 by email: dherndon@utmb.edu. We received no reply.
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Not described
Allocation concealment (selection bias) Unclear risk Not described
Blinding of participants and personnel (performance bias) 
 All outcomes Unclear risk Not described
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk Not described
Incomplete outcome data (attrition bias) 
 All outcomes Unclear risk The number of participants with incomplete data was not reported.
Selective reporting (reporting bias) Unclear risk No protocol could be obtained, and the trial did not report all‐cause mortality or serious adverse events.
For‐profit bias Unclear risk It was unclear how the trial was funded.
Other bias Low risk The trial appeared to be free of other components that could put it at risk of bias.