Jimenez 1995b.
Methods | Randomised clinical trial, Spain | |
Participants | 75 hospitalised adults, at nutritional risk due to low levels of albumin or body weight below 95% of ideal weight | |
Interventions | Experimental group 1: 59.1 g amino acids + 694 non‐protein calories (glucose)(n = 20)
Experimental group 2: 57.9 g amino acids + 600 non‐protein calories (glycerol)(n = 20) Experimental group 3: 56.6 g amino acids + 590 non‐protein calories (sorbitol‐xylitol)(n = 20) Control group: Conventional infusion therapy (5% glucose)(n = 15) |
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Outcomes | All‐cause mortality, complications, plasma concentrations | |
Study dates | Not stated | |
Notes | Same as Jimenez 1995a and Jimenenz 1995c. We only report experimental group 2 vs control here. We contacted the authors on 13th December 2015 by email: fjavierjimenez@telefonica.net. We received no reply. | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Not described |
Allocation concealment (selection bias) | Unclear risk | Not described |
Blinding of participants and personnel (performance bias) All outcomes | Unclear risk | Not described |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | Not described |
Incomplete outcome data (attrition bias) All outcomes | Low risk | There were no drop‐outs. |
Selective reporting (reporting bias) | Low risk | All‐cause mortality and serious adverse events were assessed. |
For‐profit bias | Low risk | The trial was funded by the Spanish Ministry of Health. |
Other bias | Low risk | The trial appeared to be free of other components that could put it at risk of bias. |