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. 2017 May 19;2017(5):CD011598. doi: 10.1002/14651858.CD011598.pub2

Kawaguchi 2008.

Methods Randomised clinical trial, Japan
Participants 29 hospitalised adults with cirrhosis, at nutritional risk due to the trialist indication
Male:Female = 18:11
Mean age = 63.2 years
 Exclusion criteria: Ascites or renal failure
Interventions Experimental group: Supplement 200 kcal(n = 18)
 Control group: No energy supplied (fasting)(n = 11)
Outcomes Self‐rating questionnaire (physical symptoms and mental symptoms), biochemical parameters, CT or MRI.
Study dates April 2005 to July 2006
Notes We contacted the authors on 19th August 2015 by email: takumi@med.kurume‐u.ac.jp . We received no reply.
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Not described
Allocation concealment (selection bias) Unclear risk Not described
Blinding of participants and personnel (performance bias) 
 All outcomes Unclear risk Not described
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk Not described
Incomplete outcome data (attrition bias) 
 All outcomes Unclear risk The number of participants with incomplete data was not reported.
Selective reporting (reporting bias) Unclear risk No protocol could be obtained and the trial did not report on all‐cause mortality or serious adverse events.
For‐profit bias Low risk The trial was funded by grants from the Ministry of Education, Culture, Sports, Science and Technology, Japan, the Vehicle Racing Commemorative Foundation, Japan, and the Ishibashi Foundation for the Promotion of Science, Japan.
Other bias Low risk The trial appeared to be free of other components that could put it at risk of bias.