Skip to main content
. 2017 May 19;2017(5):CD011598. doi: 10.1002/14651858.CD011598.pub2

Keele 1997.

Methods Randomised clinical trial, UK
Participants 100 hospitalised adults admitted for major abdominal surgery, at nutritional risk due to major abdominal surgery
Male:female = 48:38 (gender not reported for 14)
Mean age: 62.5 years
Interventions Experimental group: Standard ward diet + oral supplements (200 ml (1.5 kcal/ml and 0.05 g protein/ml)(n = 47)
Control group: Standard ward diet(n = 53)
Outcomes All‐cause mortality, complications, nutritional status, anthropometrics, hand‐grip strength
Study dates Not stated
Notes We could obtain no contact information for the authors.
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Not described
Allocation concealment (selection bias) Unclear risk Not described
Blinding of participants and personnel (performance bias) 
 All outcomes Unclear risk Not described
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk Not described
Incomplete outcome data (attrition bias) 
 All outcomes High risk There were above 5% dropouts, and the trial did not use proper intention‐to‐treat analysis.
Selective reporting (reporting bias) Low risk Both all‐cause mortality, and serious adverse events were reported.
For‐profit bias High risk The trial was funded by Nutricia research, which might have a conflict of interest.
Other bias Low risk The trial appeared to be free of other components that could put it at risk of bias.