Skip to main content
. 2017 May 19;2017(5):CD011598. doi: 10.1002/14651858.CD011598.pub2

Li 1998.

Methods Randomised clinical trial, China
Participants 20 hospitalised adults undergoing resection of pancreas and duodenum, at nutritional risk due to major surgery
Male:Female = 16:4
Mean age = 56 years
Exclusion criteria: Unclear
Interventions Experimental group: TPN through central vein from the 1st day after surgery for 7 days. The calorie was 125.52 ˜ 146 KJ/(kg/day), of which 35% ˜ 40% was provided by 10% Interlipid and others by glucose. Nitrogen supply was 0.2 g/kg/day ) provided by 15‐HBC (Tianjin amino acid); vitamin and trace elements(SSPC) were supplied as conventional amount; water and electrolyte according to the balance of intake and output. All nutrients were mixed in an infusion bag, and distributed uniformly over 24 hrs. (n = 10)
Control group: Conventional infusion: 200 g glucose calorie by 10% glucose liquid, without exogenous nitrogen supply, for 7 days(n = 10)
Outcomes Weight, triceps skinfold thickness, arm circumference, and nitrogen balance
Study dates Not stated
Notes We contacted the author by phone 3 times, but he had no time to answer.
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Not described
Allocation concealment (selection bias) Unclear risk Not described
Blinding of participants and personnel (performance bias) 
 All outcomes High risk Participants and personnel were not blinded.
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk The procedure of blinding was insufficiently described.
Incomplete outcome data (attrition bias) 
 All outcomes Unclear risk The numbers and reasons for withdrawals and dropouts were not clearly stated.
Selective reporting (reporting bias) Unclear risk No protocol could be obtained and the trial dit not report on all‐cause mortality or serious adverse events.
For‐profit bias Unclear risk It was unclear how the trial was funded.
Other bias Low risk The trial appeared to be free of other components that could put it at risk of bias.