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. 2017 May 19;2017(5):CD011598. doi: 10.1002/14651858.CD011598.pub2

Lough 1990.

Methods Randomised clinical trial, UK
Participants 29 hospitalised adults undergoing bone marrow transplantation
Male:Female = 20:9
Mean age = 69
Exclusion criteria: none stated
Interventions Experimental group: TPN as a solution of dextrose (50%), intralipid (20%), amino acid (8.5%), sodium, potassium, magnesium, SolivitoH, Vitlipid; Addamel for 14 days (n = 14)
Control group: 5% dextrose solution for 14 days (n = 15)
Co‐intervention: standard care including standard oral diet
Outcomes Weight, albumin, transferrin, mortality
Study dates Not stated
Notes We found no contact information for the authors.
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Not described
Allocation concealment (selection bias) Unclear risk The envelopes were described as sealed but it was unclear if they were opaque.
Blinding of participants and personnel (performance bias) 
 All outcomes Unclear risk Not described
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk Not described
Incomplete outcome data (attrition bias) 
 All outcomes Unclear risk It was unclear how many participants had incomplete outcome data
Selective reporting (reporting bias) Unclear risk The trial reports survival at 100 days but does not report complications in general terms
For‐profit bias Unclear risk It was unclear how the trial was funded
Other bias Low risk The trial appeared to be free of other components that could put it at risk of bias