Peng 2001.
Methods | Randomised clinical trial, China | |
Participants | 22 hospitalised adults admitted with severe burn injuries (TBSA > 50%), at nutritional risk due to trauma Male:Female = 15:7 Mean age = 31 years Exclusion criteria: moderate‐to‐severe inhalation injury, diarrhoea or ileus |
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Interventions | Experimental group: Early enteral feeding. Participants were given ENSURE (carbohydrate 54.5%, protein 14%, lipid 31.5%) oral or nasal feeding. 78 ‐ 80 ml/3hr, 0.75 Kcal/ml in first 24 hrs after burn, 100 ‐ 150 ml/3hr, 0.75 ‐ 1 Kcal/ml within the next 24 hrs.(n = 13) Control group: Delayed enteral feeding. Oral liquid diet 48 hrs after burn(n = 9) Co‐intervention: Conventional therapy |
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Outcomes | Plasma, endotoxin TNF‐α, urine mannitol, urinary lactulose | |
Study dates | Not stated | |
Notes | We tried and failed 3 times to contact the author by phone. | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Not described |
Allocation concealment (selection bias) | Unclear risk | Not described |
Blinding of participants and personnel (performance bias) All outcomes | High risk | Participants and personnel were not blinded. |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | Not described |
Incomplete outcome data (attrition bias) All outcomes | Unclear risk | The number of participants with incomplete data was not reported. |
Selective reporting (reporting bias) | Unclear risk | No protocol could be obtained and the trial did not report on all‐cause mortality or serious adverse events. |
For‐profit bias | Unclear risk | It was unclear how the trial was funded. |
Other bias | Low risk | The trial appeared to be free of other components that could put it at risk of bias. |