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. 2017 May 19;2017(5):CD011598. doi: 10.1002/14651858.CD011598.pub2

Pupelis 2001.

Methods Randomised clinical trial, Latvia
Participants 60 hospitalised adults undergoing surgery for peritonitis and severe pancreatitis. None of the included participants received TPN before surgery. At nutritional risk due to major surgery
Male:Female = 45:15
Mean age = 51.4 years
Exclusion criteria: none specified
Interventions Experimental group: Jejunal feeding was started during the 1st 12 hrs postoperatively in the ICU with full‐strength whole‐protein formula (1 kcal/mL) or oligopeptide‐based formula (1 kcal/mL), providing at least 300 mL each day.(n = 30)
Control group: Standard intravenous fluids(n = 30)
Outcomes Complications, SIRS, death caused by multiple organ dysfunction syndrome, mortality
Study dates January 1997 to April 1999
Notes We contacted the authors on 23rd June 2015 by email: pupelis@gailes.lv. We received no reply.
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Not described
Allocation concealment (selection bias) Unclear risk Not described
Blinding of participants and personnel (performance bias) 
 All outcomes High risk Only the experimental group received a tube.
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk Not described
Incomplete outcome data (attrition bias) 
 All outcomes Unclear risk The number of participants with incomplete data was not reported.
Selective reporting (reporting bias) Low risk No protocol was found. Serious adverse events and all‐cause mortality were reported.
For‐profit bias High risk The trial was funded by Amaija ltd. (Nutrition manufacturer).
Other bias Low risk The trial appeared to be free of other components that could put it at risk of bias.