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. 2017 May 19;2017(5):CD011598. doi: 10.1002/14651858.CD011598.pub2

Sharma 2013.

Methods Randomised clinical trial, UK
Participants 55 hospitalised adults undergoing colorectal surgery, at nutritional risk due to major gastro‐intestinal surgery
Male:Female = 35:20
Mean age = 66
Exclusion criteria: Dementia, lactose intolerance, pregnancy, diabetes mellitus, age under 16, musculoskeletal conditions preventing accurate use of the hand‐grip dynamometer and unable to feed orally preoperatively. Postoperative exclusion criteria were postoperative admission to ICU or administration of TPN.
Interventions Experimental group: Received standard diet + 6 x 60 ml/day of Pro‐Cal (3.33 kcal/ml and 0.06 mg/ml of protein) for the duration of the hospital stay(n = 32)
 Control group: Received standard diet for the duration of the hospital stay (n = 30)
Outcomes Primary outcome: Muscle strength at discharge
Secondary outcome: Daily calorie intake, nausea, days to first flatus, days to first bowel movement and postoperative length of hospital stay
Study dates Between June 2007 and November 2010
Notes We contacted the authors in September 2015 by email: dr_miteshsharma@yahoo.co.uk. We received no reply.
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk Computer‐generated
Allocation concealment (selection bias) Unclear risk The envelopes were described as sealed but not opaque.
Blinding of participants and personnel (performance bias) 
 All outcomes High risk Not blinded
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk Not described
Incomplete outcome data (attrition bias) 
 All outcomes High risk 7 randomised participants were later excluded resulting in above 5% dropouts. The trial did not account for the missing participants.
Selective reporting (reporting bias) Unclear risk No protocol could be obtained and the trial did not report on all‐cause mortality or serious adverse events.
For‐profit bias Low risk "The resources of our department were utilized to conduct the study".
Other bias Low risk The trial appeared to be free of other components that could put it at risk of bias.