Simon 1988.

Methods	Randomised clinical trial, USA
Participants	34 hospitalised adults with moderate or severe alcoholic hepatitis (chronic ethanol ingestion > 80 g/day for at least 2 years and right lobe hepatomegaly), at nutritional risk according to the trialist Male:Female = 7:15(gender not reported for 12 participants) Mean age = 41.5 years (only for the severe malnourished) Exclusion criteria: acute pancreatitis, insulin‐dependent diabetes mellitus, positive HBsAg, malignancy, hypotension, congestive heart failure, sepsis, severe COPD, and recent severe trauma, surgery, mild disease or rapidly became moribund
Interventions	Experimental group: 28 days of peripheral parenteral nutrition (2 litres a day). Each litre consisted of 35 g Aminosyn, 50 g dextrose, 500 ml of 10% Intralipid a day for a total of 1070 intravenous calories a day.(n = 16) Control group: no intervention(n = 18) Co‐interventions: diet consisting of 2400 calories and 100 g protein + can of Ensure
Outcomes	Biochemistry, grade of encephalopathy, mortality, ascites, function tests
Study dates	Not stated
Notes	We contacted the authors on 19th August 2015 by email: jgalamb@emory.edu. We received no reply.
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Not described
Allocation concealment (selection bias)	Unclear risk	The trial used sealed envelopes, but they were not described as being opaque.
Blinding of participants and personnel (performance bias) All outcomes	High risk	The trial was described as "lack of blinding".
Blinding of outcome assessment (detection bias) All outcomes	High risk	The trial was described as "lack of blinding".
Incomplete outcome data (attrition bias) All outcomes	Unclear risk	The number of participants with incomplete data was not reported.
Selective reporting (reporting bias)	Unclear risk	No protocol could be obtained, and the trial did not report on serious adverse events.
For‐profit bias	Unclear risk	It was unclear how the trial was funded.
Other bias	Low risk	The trial appeared to be free of other components that could put it at risk of bias.