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. 2017 May 19;2017(5):CD011598. doi: 10.1002/14651858.CD011598.pub2

Soop 2004.

Methods Randomised clinical trial, Sweden/UK
Participants 20 hospitalised adults undergoing elective major colorectal surgery, at nutritional risk due to major surgery
Male:Female = 12:6 (gender not reported for two participants)
Mean age = 62 years
Exclusion criteria: age below 18 years or above 80 years; BMI below 18 or above 30 kg/m2
Interventions Experimental group: Immediate postoperative enteral nutrition with an energy‐dense residue‐free solution (1·5 kcal/ml Nutrison Energy, Nutricia)(n = 10)
 Control group: Immediate postoperative enteral nutrition with a hypocaloric solution with an indistinguishable appearance (0·2 kcal/ml Nutricia)(n = 10)
Outcomes Urinary nitrogen losses, insulin resistance, blood glucose, complication and hospital stay
Study dates Not stated
Notes We contacted the authors in December 2015 by email: mattias.soop@mac.com. We received an initial reply but no further information was supplied.
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Not described
Allocation concealment (selection bias) Unclear risk Not described
Blinding of participants and personnel (performance bias) 
 All outcomes Low risk The control group received a solution with an indistinguishable appearance.
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk Not described
Incomplete outcome data (attrition bias) 
 All outcomes Low risk There were no dropouts.
Selective reporting (reporting bias) Unclear risk No protocol could be obtained and the trial did not report all‐cause mortality or serious adverse events.
For‐profit bias High risk Financial support from Numico Research.
Other bias Low risk The trial appeared to be free of other components that could put it at risk of bias.