Wang 2011b.
Methods | Randomised clinical trial, China | |
Participants | 79 hospitalised adult with AIDS, at nutritional risk due to surgery or mechanical ventilation Male:Female = 41:38 Mean age = 38.2 years Exclusion criteria: diabetes mellitus, hyperthyroidism, severe liver and kidney dysfunction, CD4 cell count > 200 /μl |
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Interventions | Experimental group: Enteral nutrition of non‐protein calorie 84 kJ/(kg/day), nitrogen 0.2 g/(kg/day). Participants received a guaranteed calorie intake every day of 83.6 ~ 146.3 kJ/(kg/day). The course of treatment was 5 ˜ 7 days. (n = 46) Control group: no intervention (n = 33) Co‐interventions: conventional treatment (glucose and saline as intravenous infusion) |
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Outcomes | T lymphocytes (CD3, CD4, and CD8), blood biochemical parameters. | |
Study dates | Not stated | |
Notes | We contacted the authors on email: docwang@126.com. We received no reply. | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Low risk | The sequence generation was achieved using a random‐numbers table. |
Allocation concealment (selection bias) | Unclear risk | Not described |
Blinding of participants and personnel (performance bias) All outcomes | High risk | Participants and personnel were not blinded. |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | Not described |
Incomplete outcome data (attrition bias) All outcomes | Unclear risk | The number of participants with incomplete data was not reported. |
Selective reporting (reporting bias) | Unclear risk | No protocol could be obtained and the trial did not report on all‐cause mortality or serious adverse events. |
For‐profit bias | Unclear risk | It was unclear how the trial was funded. |
Other bias | Low risk | The trial appeared to be free of other components that could put it at risk of bias. |