Skip to main content
. 2017 May 19;2017(5):CD011598. doi: 10.1002/14651858.CD011598.pub2

Wang 2013a.

Methods Randomised clinical trial, China
Participants 48 hospitalised adults with colorectal cancer, at nutritional risk due to major surgery
Male:Female = 27:21
Age range = 37 ‐ 73 years
Exclusion criteria: Older than 80, received chemotherapy prior to the surgery, serious organ function disorder, low rectal cancer and having abdominoperineal resection, palliative operation, or emergency operation, severely obese, fatty or malnourished, metabolic and endocrine diseases such as hyperthyroidism 7, having Intestinal obstruction, perforation, or intestinal necrosis
Interventions Experimental group: Enteral nutrition: 500 ml Jevity each day was taken orally from the 1st day of admission to the hospital (500 ml Jevity contained 2196.6 KJ, protein 20 g, fat 17 g, carbohydrate 70 g and dietary fibre 5.3 g). A nasal tube was placed after the surgery, and water was given at the 1st postoperative day, and if there was no discomfort, 500 ml Jevity and water were administered on the 2nd postoperative day. From the 3rd day on, 1000 ml Jevity was given with certain nutrition liquid diet until hospital discharge. If the participants had symptoms like nausea, vomiting or abdominal distention, the dose of Jevity would be decreased or changed to another kind of nutrient.(n = 24)
Control group: Standard usual care. Participants were administered venous transfusion after the surgery, and water was given after anal‐exsufflation. If there was no discomfort, the volume of water would be increased and a liquid diet considered. (n = 24)
Outcomes Postoperative exhaust time, hospital stay, treatment charge, bio markers postoperative complications such as pulmonary infection, the completion rate of nutrition agents
Study dates Not stated
Notes We contacted the authors on 09th December 2015 by phone and by email: ngds0538@sina.com. We received no reply.
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk The randomisation method was random table.
Allocation concealment (selection bias) Unclear risk Not described
Blinding of participants and personnel (performance bias) 
 All outcomes High risk Participants and personnel were not blinded.
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk Not described
Incomplete outcome data (attrition bias) 
 All outcomes Unclear risk The number of participants with incomplete data was not reported.
Selective reporting (reporting bias) Unclear risk No protocol could be obtained and the trial did not report on all‐cause mortality or serious adverse events.
For‐profit bias Unclear risk It was unclear how the trial was funded.
Other bias Low risk The trial appeared to be free of other components that could put it at risk of bias.