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. 2017 May 19;2017(5):CD011598. doi: 10.1002/14651858.CD011598.pub2

Watters 1997.

Methods Randomised clinical trial, Canada
Participants 31 hospitalised adults undergoing oesophagectomy or pancreatoduodenectomy, at nutritional risk due to major abdominal surgery
Male:Female = 22:6 (analysed participants only)
Mean age = 62.5
Exclusion criteria: Metastases identified before surgery or at the time of surgery, diabetes mellitus,and corticosteroid use
Interventions Experimental group: Immediate postoperative enteral feeding (The enteral preparation provided 4.4 g protein and 445 kJ/100 mL) (n = 15)
 Control group: No enteral feeding during the 1st 6 postoperative days (n = 16)
Co‐intervention: PEG placement
Outcomes Hand‐grip strength, spirometry, serum biochemistry, urine biochemistry, mobility
Study dates Not stated
Notes We could obtain no contact information for the authors.
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk The sequence generation was computer‐generated.
Allocation concealment (selection bias) Low risk The allocation was concealed in sealed envelopes.
Blinding of participants and personnel (performance bias) 
 All outcomes High risk The participants and personnel were unblinded.
Blinding of outcome assessment (detection bias) 
 All outcomes High risk The outcome assessment was unblinded.
Incomplete outcome data (attrition bias) 
 All outcomes High risk There were above 5% dropouts, and the trial did not allow proper intention‐to‐treat methodology.
Selective reporting (reporting bias) Unclear risk No protocol could be obtained, and all‐cause mortality was not reported.
For‐profit bias Unclear risk It was unclear how the trial was funded.
Other bias Low risk The trial appeared to be free of other components that could put it at risk of bias