Young 1989a.
Methods | Randomised clinical trial, UK | |
Participants | 30 hospitalised adults with gastro‐intestinal neoplasms, at nutritional risk due to having lost more than 5 kg of weight over the last 3 months Male:Female = 21:9 Mean age = 65 years |
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Interventions | Experimental group: Group A) IVN for 3 days (0.18 g N/kg/day as amino acid; 30 kcal/kg/day as glucose)(n = 10) Group B) IVN for 7 days (n = 10) Control group: Standard hospital diet (n = 10) |
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Outcomes | Plasma proteins, plasma amino acids, liver protein synthesis rate | |
Study dates | Not stated | |
Notes | Same trial as Young 1989b with the results from experimental Group (A) vs control. We could obtain no contact information for the authors. | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Not described |
Allocation concealment (selection bias) | Unclear risk | Not described |
Blinding of participants and personnel (performance bias) All outcomes | Unclear risk | Not described |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | Not described |
Incomplete outcome data (attrition bias) All outcomes | Unclear risk | The number of participants with incomplete data was not reported. |
Selective reporting (reporting bias) | High risk | No protocol could be obtained and the trial did not report on all‐cause mortality or serious adverse events. |
For‐profit bias | Unclear risk | It was unclear how the trial was funded. |
Other bias | Low risk | The trial appeared to be free of other components that could put it at risk of bias. |