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. 2017 May 19;2017(5):CD011598. doi: 10.1002/14651858.CD011598.pub2

Zhao 2014.

Methods Randomised clinical trial, China
Participants 64 hospitalised adults with acute non‐lymphocytic leukaemia, at nutritional risk according to trialist indication
Male:Female = not stated
Mean age = 32.8 years
Exclusion criteria: acute disease exacerbation; chronic diseases such as concomitant with diabetes, hypertension, liver and kidney dysfunction; concomitant with serious allergy and other immune system diseases; pregnant or lactating; within 6 months after surgery; end‐stage leukaemia
Interventions Experimental group: Standard nutrition support provided to the participants with established nutrition risk (NRS‐2002 ≥ 3) during the next chemotherapy course. The participants should have high protein and high energy intake 3 days before and 1 week after chemotherapy, which was achieved with oral Enteral Nutritional Powder (TP) 40 g.
 The nutrition support protocol of “allowable intake inadequacy” of relatively lower energy (80% of required energy) should consist of oral Enteral Nutritional Powder (TP) 30 g, twice a day, as supplementation.(n = 32)
Control group: Standard hospital diet(n = 32)
Outcomes Prealbumin, haemoglobin, red blood cell, albumin, total protein, BMI
Study dates Not stated
Notes We had trouble understanding the language in this trial, hence limited descriptions. We contacted the authors on 25th September 2015 by email: zhuzhiming6542@sina.com. We received no reply.
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Not described
Allocation concealment (selection bias) Unclear risk Not described
Blinding of participants and personnel (performance bias) 
 All outcomes Unclear risk Not described
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk Not described
Incomplete outcome data (attrition bias) 
 All outcomes Unclear risk The number of participants with incomplete data was not reported.
Selective reporting (reporting bias) Unclear risk No protocol could be obtained and the trial did not report all‐cause mortality or serious adverse events.
For‐profit bias Low risk Trial was supported by the Creative Foundation of Navy General Hospital (CX201113).
Other bias Low risk The trial appeared to be free of other components that could put it at risk of bias.