Zhu 2000.
Methods | Randomised clinical trial, China | |
Participants | 98 hospitalised adults undergoing gastric operation, at nutritional risk due to having major surgery Male:Female = 60:38 Mean age = 47.8 years |
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Interventions | Experimental group: Enteral nutrition support. On the 1st day a half‐dose, 66.9 Kj/kg/day, dripping speed of 60 ‐ 100 ml/hr; increased on the 2nd day up to full dose, dripping speed of 120 ‐ 150 ml/hr through nasal‐jejunum tube for 7 days.(n = 48) Control group: Conventional infusion of 2494.4 Kj/day and without protein for 7 days after operation (n = 50) |
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Outcomes | Serum cytokine levels (IL‐2, IFN‐γ, IL‐2Rα, sIL‐2R) | |
Study dates | Not stated | |
Notes | We tried but failed to contact the authors were att by phone. | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Not described |
Allocation concealment (selection bias) | Unclear risk | Not described |
Blinding of participants and personnel (performance bias) All outcomes | High risk | Not mentioned, but the trial compared fluid infusion with enteral nutrition, which can be judged as high risk of bias |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | Not described |
Incomplete outcome data (attrition bias) All outcomes | Unclear risk | The numbers and reasons for withdrawals and dropouts were not clearly stated or not stated at all. |
Selective reporting (reporting bias) | Unclear risk | There is no protocol and the outcomes all‐cause mortality and serious adverse events are not reported on. |
For‐profit bias | Unclear risk | It was unclear how the trial was funded. |
Other bias | Low risk | The trial appeared to be free of other components that could put it at risk of bias. |