Zhu 2002a.
Methods | Randomised clinical trial, China | |
Participants | 42 hospitalised adults undergoing gastric operation, at nutritional risk due to major surgery Male:Female = 29:13 Mean age = 58.6 years Exclusion criteria: Metabolic and endocrine diseases, abnormal liver or kidney function |
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Interventions | Experimental group: Enteral nutrition support. The amount of calories was 125.5 kJ (30 kcal)/(kg/day), and nitrogen was 0.2 g/(kg/day). It was given through a nasal‐duodenal tube for 7 days (half‐dose for the first 2 days).The nutrition was provided by Nutrition Fiber (protein 20 g, fat 19.5 g,carbohydrate 61.5 g, minerals 3 g, food fibre 7.5 g, energy 4.18 Kj(1 kcal)/ml per 500ml).(n = 24) Control group: Conventional infusion which consisted of 5% ‐ 10% glucose, electrolytes, and vitamins, about 2500 kJ (600 kcal)/day, without exogenous nitrogen (n = 18) |
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Outcomes | All‐cause mortality, severe complications, adverse events, nutritive index including body weight, biochemical index, immune index (IgA, IgM, IgG,lymphocyte). | |
Study dates | Not stated | |
Notes | The authors were attempted contacted by phone. No contact was made. | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Not described |
Allocation concealment (selection bias) | Unclear risk | Not described |
Blinding of participants and personnel (performance bias) All outcomes | High risk | Participants and personnel were not blinded. |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | Not described |
Incomplete outcome data (attrition bias) All outcomes | Unclear risk | The number of participants with incomplete data was not reported. |
Selective reporting (reporting bias) | Low risk | No protocol could be obtained but the trial did report on all‐cause mortality and serious adverse event. |
For‐profit bias | Unclear risk | It was unclear how the trial was funded. |
Other bias | Low risk | The trial appeared to be free of other components that could put it at risk of bias. |