Comparison 3.
Pre‐prandial versus post‐prandial glucose monitoring
| Outcome or subgroup title | No. of studies | No. of participants | Statistical method | Effect size |
|---|---|---|---|---|
| 1 Pre‐eclampsia | 1 | 58 | Risk Ratio (M‐H, Fixed, 95% CI) | 6.43 [0.82, 50.11] |
| 2 Caesarean section | 1 | 61 | Risk Ratio (M‐H, Fixed, 95% CI) | 1.45 [0.92, 2.28] |
| 3 Large‐for‐gestational age | 1 | 61 | Risk Ratio (M‐H, Fixed, 95% CI) | 1.16 [0.73, 1.85] |
| 4 Perinatal mortality | 1 | 61 | Risk Ratio (M‐H, Fixed, 95% CI) | 2.91 [0.12, 68.66] |
| 5 Weight gain during pregnancy | 1 | 61 | Mean Difference (IV, Fixed, 95% CI) | ‐0.90 [‐3.86, 2.06] |
| 6 Insulin dose | 1 | 61 | Mean Difference (IV, Fixed, 95% CI) | ‐17.40 [‐43.41, 8.61] |
| 7 Glycaemic control ‐ Insulin dose | 1 | 61 | Mean Difference (IV, Fixed, 95% CI) | ‐0.20 [‐0.45, 0.05] |
| 8 Glycaemic control ‐ HbA1c | 1 | 61 | Mean Difference (IV, Fixed, 95% CI) | 0.30 [‐0.08, 0.68] |
| 9 Stillbirth | 1 | 61 | Risk Ratio (M‐H, Fixed, 95% CI) | 2.91 [0.12, 68.66] |
| 10 Gestational age at birth | 1 | 61 | Mean Difference (IV, Fixed, 95% CI) | 0.20 [‐0.84, 1.24] |
| 11 Preterm birth < 37 weeks | 1 | 61 | Risk Ratio (M‐H, Fixed, 95% CI) | 1.33 [0.62, 2.84] |
| 12 Macrosomia | 1 | 61 | Risk Ratio (M‐H, Fixed, 95% CI) | 2.18 [0.75, 6.32] |
| 13 Birthweight | 1 | 61 | Mean Difference (IV, Fixed, 95% CI) | 0.24 [‐0.10, 0.58] |
| 14 Adiposity ‐ Subscapula skinfold thickness | 1 | 61 | Mean Difference (IV, Fixed, 95% CI) | 0.60 [‐0.18, 1.38] |
| 15 Adiposity ‐ Triceps skinfold thickness | 1 | 61 | Mean Difference (IV, Fixed, 95% CI) | 0.60 [0.04, 1.16] |
| 16 Birth trauma (shoulder dystocia, bone fracture, nerve palsy) (not pre‐specified as a composite) | 1 | 61 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.48 [0.05, 5.06] |
| 17 Respiratory distress syndrome | 1 | 61 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.97 [0.06, 14.78] |
| 18 Neonatal hypoglycaemia | 1 | 61 | Risk Ratio (M‐H, Fixed, 95% CI) | 1.09 [0.48, 2.45] |
| 19 Neonatal jaundice (hyperbilirubinaemia) | 1 | 61 | Risk Ratio (M‐H, Fixed, 95% CI) | 1.16 [0.40, 3.40] |
| 20 Cord IGF‐1 | 1 | 61 | Mean Difference (IV, Fixed, 95% CI) | 1.30 [‐0.70, 3.30] |
| 21 Neonatal glucose at age 1 hour (not pre‐specified) | 1 | 61 | Mean Difference (IV, Fixed, 95% CI) | ‐0.20 [‐0.88, 0.48] |
| 22 Transient tachypnea (not pre‐specified) | 1 | 61 | Risk Ratio (M‐H, Fixed, 95% CI) | 2.58 [0.76, 8.81] |
| 23 Neonatal intensive care admissions | 1 | 59 | Risk Ratio (M‐H, Fixed, 95% CI) | 1.04 [0.62, 1.74] |