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MSRB3 rs61921502 risk allele and MsrB3-IR in hippocampal white matter (WM) arteriolar walls in 10 FHS participants- brain donors. Solid symbols represent AD patients (CDR1-3, BB IV-VI), empty symbols are either cognitively intact (CDR 0) or have mild cognitive deficit (CDR 0.5) and early AD pathology (Braak I-III). Colored symbols represent subjects with APOE4 subjects, a trait that appears to exhibit an organized pattern according to the presence of MSRB3 rs61921502 risk allele.
